首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Diabetes, aging and physical activity
Authors:Bruce Frier  Pearl Yang  Albert W Taylor
Institution:(1) School of Kinesiology, The University of Western Ontario, London, Ontario, Canada;(2) Graduate Department of Rehabilitation Science, University of Toronto, Toronto, Canada;(3) Faculty of Health Sciences, The University of Western Ontario, London, Ontario, Canada;(4) Faculty of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada;(5) The Canadian Centre for Activity and Aging, London, Ontario, Canada
Abstract:Diabetes mellitus (DM) is a metabolic disease affecting the regulation of insulin and glucose causing a disruption in the normal control of counterregulatory hormones and macronutrients, resulting in blood glucose accumulation. Metabolic deregulation leads to the production of noxious substances that have a particular propensity for damaging vascular and nervous structures. Physiological changes observed with aging are correlated with a concomitant increase in DM and its associated complications. Long-term complications, including peripheral and central neuropathies, micro- and macrovascular damage, retinopathy, and nephropathy are the major causes of mortality in diabetics cardiovascular disease (CVD) being the primary complication causing death in this population]. All-cause mortality is three to four times greater in the DM population; hence, management of DM is of timely importance, particularly with a projected prevalence increase of 134% within the next 25 years among individuals over the age of 65 years. Exercise modalities, including endurance and resistance training, were employed to improve glycemic/metabolic control and to ameliorate the progression of DM-related complications. Several risk factors, including glucose levels, blood pressure, lipid/cholesterol profile, and BMI, are reportedly improved with these modes of exercise. However, not all studies demonstrate an improvement in risk factors, but consistently note improvement in complications and a reduction of DM incidence. There is convincing evidence that exercise, with or without specific improvements to traditional DM-related risk factors, is an effective therapy for the management of DM.The Canadian Centre for Activity and Aging is affiliated with St. Joseph’s Health Care and The University of Western Ontario, London, Ontario, Canada.
Keywords:Exercise  Diabetes mellitus  Type 1  Type 2  Diabetes complications
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号