| 4—(2—氨乙基)哌嗪酮单盐酸盐的合成 |
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| 引用本文： | 曲荣君,石明理.4—(2—氨乙基)哌嗪酮单盐酸盐的合成[J].鲁东大学学报,1991(2). |
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| 作者姓名： | 曲荣君 石明理 |
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| 作者单位： | 烟台师范学院化学系
(曲荣君)，山东师范大学(石明理) |
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| 摘 要： | 以二乙烯三胺、邻笨二甲酐和溴乙酸乙酯为原料合成了4-(2-氨乙基)哌嗪酮单盐酸盐。产品的纯度通过了元素分析,结构经红外光谱、核磁共振谱证实,合成中,将溶解性极强的N,N-二甲基甲酰胺改为非极性的甲苯,将催化剂由无水碳酸钾改为过量的反应物本身,杂质和未反应物因溶解度小而除去,大大简化了产品的纯化过程,提高了产品的转化率。
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| 关 键 词： | 4-(2-氨乙基)哌嗪酮单盐酸盐 合成 元素分析 |
SYNTHESIS OF 4- (2-AMNOETHYLENE) -2-OXOPIPERAZINE HYDROCHLORATE |
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| Qu Rongjun Shi Mingli.SYNTHESIS OF 4- (2-AMNOETHYLENE) -2-OXOPIPERAZINE HYDROCHLORATE[J].Ludong University Journal (Natural Science Edition),1991(2). |
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| Authors: | Qu Rongjun Shi Mingli |
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| Institution: | Qu Rongjun Shi Mingli
(Department of Chemistry) (Shangdong Normal University) |
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| Abstract: | 4- (2 - aminoethylene) - 2 - oxopiperazine hydrochlorate(E) is synthesized by taking phthatic anhydride,diethylenetriamine and ethyl bromoacetate as the materials. The strueture of product is identified by IR and 1HNMR spectrum. In the process of synthesis anhydrous K2CO3 and DMF are substituted for reactant-self and methylbenzene. |
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| Keywords: | 4- (2-aminoethylene) - 2-oxopiperazine hyarochlorate synthesis elemental analysis |
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