Pool Screening: An Example of Independent Nonidentical Bernoulli Trial |
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| Authors: | Hongjiang Gao Inmaculada Aban Charles R. Katholi |
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| Affiliation: | 1. Division of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infections Disease, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA;2. Biostatistics Department, University of Alabama at Birmingham, , Alabama, USA |
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| Abstract: | Pool screening is a widely used study design to make inference about the probability of a subject being positive for an infection when the probability is extremely low. When the pool sizes are unequal, outcomes of pool screening follow independent nonidentical Bernoulli distributions. This paper presents different calculation methods for the probability distribution of T, the number of positive pools. Marcus and Lopes recursive method is recommended. |
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| Keywords: | Number of positive pools Pool screening Recursive method. |
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