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Joint model for bivariate zero-inflated recurrent event data with terminal events
Authors:Yang-Jin Kim
Institution:Department of Statistics, Sookmyung Women''s University, Seoul, South Korea
Abstract:Bivariate recurrent event data are observed when subjects are at risk of experiencing two different type of recurrent events. In this paper, our interest is to suggest statistical model when there is a substantial portion of subjects not experiencing recurrent events but having a terminal event. In a context of recurrent event data, zero events can be related with either the risk free group or a terminal event. For simultaneously reflecting both a zero inflation and a terminal event in a context of bivariate recurrent event data, a joint model is implemented with bivariate frailty effects. Simulation studies are performed to evaluate the suggested models. Infection data from AML (acute myeloid leukemia) patients are analyzed as an application.
Keywords:Bivariate recurrent event  cure rate model  frailty effect  joint model  piecewise baseline  terminal event
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