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Treatment design selection effects on parameter estimation in dynamic logistic models for longitudinal binary data
Abstract:In a longitudinal set-up, to examine the effects of certain fixed covariates on the repeated binary responses, there exists an approach to model the binary probabilities through a dynamic logistic relationship. In some practical situations such as in longitudinal clinical studies, it may happen that some of the covariates such as treatments are selected randomly following an adaptive design, whereas the rest of the covariates may be fixed by nature. The purpose of this study is to examine the effects of the design weights selection on the parameter estimation including the treatment effects, after taking the longitudinal correlations of the repeated binary responses into account.
Keywords:conditional and unconditional correlations  consistency and efficiency  lagged dependence  multiple treatments  regression effects  repeated binary responses  time-dependent covariates  time independent treatment covariates
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