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A Simple Approach to Fitting Bayesian Survival Models
Authors:Gustafson  Paul  Aeschliman  Dana  Levy  Adrian R
Institution:(1) Department of Statistics, University of British Columbia, Vancouver, B.C., Canada;(2) Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital, Vancouver, B.C., Canada;(3) Department of Health Care and Epidemiology, University of British Columbia, Vancouver, B.C., Canada
Abstract:There has been much recent work on Bayesian approaches to survival analysis, incorporating features such as flexible baseline hazards, time-dependent covariate effects, and random effects. Some of the proposed methods are quite complicated to implement, and we argue that as good or better results can be obtained via simpler methods. In particular, the normal approximation to the log-gamma distribution yields easy and efficient computational methods in the face of simple multivariate normal priors for baseline log-hazards and time-dependent covariate effects. While the basic method applies to piecewise-constant hazards and covariate effects, it is easy to apply importance sampling to consider smoother functions.
Keywords:Bayesian survival analysis  copula model  Markov chain Monte Carlo  semiparametric hazard  time-dependent covariate effects
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