| 基于多基因组合选择模型的结肠癌特征基因选取 |
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| 引用本文： | 马超.基于多基因组合选择模型的结肠癌特征基因选取[J].统计与信息论坛,2012,27(6):78-82. |
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| 作者姓名： | 马超 |
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| 作者单位： | 南京大学 公共卫生管理与医疗保障政策研究中心,江苏南京,210093 |
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| 摘 要： | 通过基因的Bhattacharyya距离指标过滤掉大部分无关基因,然后探索性的提出了一种建立多基因组合选择模型的统计方法.从候选特征基因中选取了8个可能的结肠癌特征基因集合,判别分析的结果证明了该方法的可行性.
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| 关 键 词： | 基因表达谱 生物信息学 多基因组合选择模型 结肠癌 |
Informative Genes Selection of Colon Cancer Based on Polygenic Combination Selection Model |
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| MA Chao.Informative Genes Selection of Colon Cancer Based on Polygenic Combination Selection Model[J].Statistics & Information Tribune,2012,27(6):78-82. |
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| Authors: | MA Chao |
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| Institution: | MA Chao (Center for Health Management and Care Security Policy Research,Nanjing University,Nanjing 210093,China) |
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| Abstract: | To select informative genes of colon cancer by analysis of gene expression.Most irrelevant gene filtration by the gene distance method of Bhattacharyya,then putting forward a statistical method of establishing polygenic combination selection model.The study selects 8 possible informative genes sets of colon cancer from the candidate informative genes.The results of discriminant analysis show the feasibility of this approach,and play a certain reference arriving role to clinical diagnosis of cancer and research in biomedical sciences. |
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| Keywords: | DNA microarray Bioinformatics polygenic combination selection model colon cancer |
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