| 短波近红外漫反射光谱法对氨苄西林粉末药品的非破坏定量分析 |
| |
| 引用本文： | 王桂芳,王彬,陈庆先,孙丽丽,任玉林.短波近红外漫反射光谱法对氨苄西林粉末药品的非破坏定量分析[J].福建农林大学学报(哲学社会科学版),2007(12). |
| |
| 作者姓名： | 王桂芳 王彬 陈庆先 孙丽丽 任玉林 |
| |
| 作者单位： | 白城医学高等专科学校 白城137000(王桂芳)，吉林大学化学学院 长春130023(王彬，任玉林)，白城市食品药品检测所 白城137000(陈庆先，孙丽丽) |
| |
| 基金项目： | 吉林省科技厅项目基金(批准号:20030607-2) |
| |
| 摘 要： | 本文采用短波近红外漫反射光谱法对氨苄西林粉末药品中主要成分氨苄西林进行快速、无损非破坏快速定量分析。采用偏最小二乘法(PLS)建立近红外光谱信息与待测组分含量间的最佳数学校正模型。讨论了光谱的预处理方法和主成分数对PLS定量预测能力的影响,并对预测集样品含量进行预测,得到了较为满意的结果。
|
| 关 键 词： | 短波近红外光谱法 偏最小二乘法(PLS) 非破坏定量分析 氨苄西林粉末药品 |
Non-destructive Analysis of Ampicillin Powder by Use of Short-wavelength Near-infrared Spectroscopy |
| |
| Guifang Wang,Bin Wang,Qingxian Chen,Lili Sun,Yulin Ren.Non-destructive Analysis of Ampicillin Powder by Use of Short-wavelength Near-infrared Spectroscopy[J].Journal of Fujian Agriculture and Forestry University,2007(12). |
| |
| Authors: | Guifang Wang Bin Wang Qingxian Chen Lili Sun Yulin Ren |
| |
| Institution: | Guifang Wang1,Bin Wang2,Qingxian Chen3,Lili Sun3,Yulin Ren2 |
| |
| Abstract: | A rapid and nondestructive method using short-wavelength near-infrared diffuse reflectance spectroscopy was presented to analysis the principal component (Ampicillin) of Ampicillin powder samples. Partial least squares (PLS) method was utilized to establish the best mathematic calibration model that for describing the relationship between the near-infrared information and each component. Furthermore the three pretreated spectra were used and compared, and the numbers of principal component's affection on the prediction ability of PLS were discussed. The prediction set was predicted, and the results were satisfied. |
| |
| Keywords: | Short-wavelength near-infrared diffuse reflectance spectroscopy Partial least squares (PLS) Non-destructive quantitative analysis Ampicillin powder |
| 本文献已被 CNKI 等数据库收录！ |
