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Biological Models of Carcinogenesis and Quantitative Cancer Risk Assessment
Authors:Suresh H. Moolgavkar
Affiliation:Fred Hutchinson Cancer Research Center, 1124 Columbia Street, MP-665, Seattle, WA 98104.
Abstract:Biologically-based models of carcinogenesis were originally developed to explain certain quanti-tative phenomena associated with carcinogenesis, and to provide a framework within which questions regarding the process could be addressed. Some limitations in the use of these models for quantitative cancer risk assessment are discussed.
Keywords:Carcinogenesis    cancer risk    biological models
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