A Linear Model for Managing the Risk of Antimicrobial Resistance Originating in Food Animals |
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| Authors: | Mary J. Bartholomew David J. Vose Linda R. Tollefson Curtis C. Travis |
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| Affiliation: | FDA Center for Veterinary Medicine, 7500 Standish Place, Rockville, MD 20855, USA. mbarthol@cvm.fda.gov |
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| Abstract: | A linear population risk model used by the U.S. Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM) estimates the risk of human cases of campylobacteriosis caused by fluoroquinolone-resistant Campylobacter. Among the cases of campylobacteriosis attributed to domestically produced chicken, the fluoroquinolone resistance is assumed to result from the use of fluoroquinolones in poultry in the United States. Properties of the linear population risk model are contrasted with those of a farm-to-fork model commonly used for microbial risk assessments. The utility of the linear population model for the purpose for which it was used by CVM is discussed. |
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| Keywords: | Campylobacter fluoroquinolones linear risk model risk analysis |
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