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Improved construction for pooling design
Authors:Ping Deng  F K Hwang  Weili Wu  David MacCallum  Feng Wang  Taieb Znati
Institution:(1) Department of Computer Science, University of Texas at Dallas, Richardson, TX 75083, USA;(2) Department of Applied Mathematics, National Chiaotung University, Hsing Chu, Taiwan;(3) Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN 55455, USA;(4) Department of Computer Science, University of Pittsburgh, Pittsburgh, PA 15215, USA
Abstract:Pooling design is a mathematical tool with many applications in molecular biology, specially to reduce the number of tests for DNA library screening. In this note, we study construction of pooling design and present an improvement to a recent new construction given by Du et al. (J. Comput. Biol. 13:990–995, 2006). P. Deng and W. Wu supported in part by National Science Foundation under grants CCF-0514796 and CNS-0524429. T. Znati supported in part by National Science Foundation under grant CCF-0548895.
Keywords:Pooling design  Transversal design  Multiplication theorem  Disjunct matrix
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