Aging-related research in the "-omics" age |
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Authors: | Kaeberlein Matt |
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Institution: | Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. kaeber@u.washington.edu |
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Abstract: | The application of high-throughput technologies to aging-related research has the potential to dramatically enhance our understanding of how longevity is determined at a molecular level. Genome-scale studies are being carried out in every major model system used for aging-related research, and new technologies are being developed to rapidly identify mutations or small-molecules that increase life span. A meta-analysis of data derived from genome-wide studies of aging in simple eukaryotes will allow the identification of conserved determinants of longevity that can be tested in mammals. |
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