Bayesian prediction for two-stage sequential analysis in clinical trials |
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| Authors: | Hayet Merabet Ahlam Labdaoui Pierre Druilhet |
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| Affiliation: | 1. Laboratory of Applied Mathematics and Modeling, Department of Mathematics, University Constantine 1, Constantine, Algeria;2. Laboratory UMR, Department of Mathematics, University Blaise Pascal, Clermont-Ferrand, France |
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| Abstract: | This article deals with a Bayesian predictive approach for two-stage sequential analyses in clinical trials, applied to both frequentist and Bayesian tests. We propose to make a predictive inference based on the notion of satisfaction index and the data accrued so far together with future data. The computations and the simulation results concern an inferential problem, related to the binomial model. |
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| Keywords: | Bayesian analysis clinical trials predictive approach sequential analysis. |
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