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Dependence Estimation Over a Finite Bivariate Failure Time Region
Authors:Fan  Juanjuan  Hsu  Li  Prentice  Ross L
Institution:(1) Department of Statistics, University of California, Davis, CA, 95616;(2) Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109
Abstract:This articleconcerns nonparametric estimation of association between bivariatefailure times. In the presence of independent right censoring,the support for failure time variates may be restricted and measuresof dependence over a finite failure time region may be of particularinterest. To this end, the reciprocal cross ratio function, weightedby the bivariate failure time density, is proposed as a summarymeasure of dependence over a failure time region. This `relativerisk' estimator is shown to be consistent and asymptoticallynormally distributed, with consistent bootstrap variance estimator.A finite-region version of Kendall's tau, which is suitable forcensored failure time data, is also proposed, and correspondingasymptotic distribution theory is noted. The accuracy of theseasymptotic approximations is studied in simulations and an illustrationis provided.
Keywords:bootstrap  censoring  correlated failure times  cross ratio function  Kendall's tau  nonparametric estimation  relative risk
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