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Maximum likelihood estimates in the multivariate normal with patterned mean and covariance via the em algorithm
Authors:Dal ton F Andrade  Ronald W Helms
Affiliation:1. Department of Quantitative Methods Embrapa , Brasilia, DF, Brasil;2. Department of Biostatistics , University of North Carolina , Chapel Hill, NC, USA
Abstract:The maximum likelihood equations for a multivariate normal model with structured mean and structured covariance matrix may not have an explicit solution. In some cases the model's error term may be decomposed as the sum of two independent error terms, each having a patterned covariance matrix, such that if one of the unobservable error terms is artificially treated as "missing data", the EM algorithm can be used to compute the maximum likelihood estimates for the original problem. Some decompositions produce likelihood equations which do not have an explicit solution at each iteration of the EM algorithm, but within-iteration explicit solutions are shown for two general classes of models including covariance component models used for analysis of longitudinal data.
Keywords:covariance components  linear models  longitudinal data analysis  mixed models  random effects  repeated measures  postage models
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