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Bayesian analysis of correlated mixed categorical data by incorporating historical prior information
Authors:Ming-Hui Chen
Institution:Department of Mathematical Sciences , Worcester Polytechnic Institute , Worcester, MA, 01609-2280, U.S.A100 Institute Road
Abstract:In this article, we develop statistical models for analysis of correlated mixed categorical (binary and ordinal) response data arising in medical and epidemi-ologic studies. There is evidence in the literature to suggest that models including correlation structure can lead to substantial improvement in precision of estimation or are more appropriate (accurate). We use a very rich class of scale mixture of multivariate normal (SMMVN) iink functions to accommodate heavy tailed distributions. In order to incorporate available historical information, we propose a unified prior elicitation scheme based on SMMVN-link models. Further, simulation-based techniques are developed to assess model adequacy. Finally, a real data example from prostate cancer studies is used to illustrate the proposed methodologies.
Keywords:Bayesian Hierarchical model  Markov chain Monte Carlo  Scale mixture of multivariatc normal links
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