Generalized linear regression models incorporating original outcome distributions

ABSTRACT

In this article, we propose an approach for incorporating continuous and discrete original outcome distributions into the usual exponential family regression models. The new approach is an extension of the works of Suissa (1991 Suissa, S. (1991). Binary methods for continuous outcomes: A parametric alternative. J. Clin. Epidemiol. 44:241–248.Crossref], PubMed], Web of Science ®] , Google Scholar]) and Suissa and Blais (1995 Suissa, S., Blais, L. (1995). Binary regression with continuous outcomes. Stat. Med. 14:247–255.Crossref], PubMed], Web of Science ®] , Google Scholar]), which present methods to estimate the risk of an event defined in a sample subspace of an original continuous outcome variable. Simulation studies are presented in order to illustrate the performance of the developed methodology. Real data sets are analyzed by using the proposed models.