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Maximum likelihood methods for complex sample data: logistic regression and discrete proportional hazards models
Authors:Lloyd E Chambless  Kerrie E Boyle
Institution:1. Department of Biostatistics School of Public Health , University of North Carolina , Chapel Hill, N.C., 27514;2. Chemical Industry Institute of Toxicology , Research Triangle Park, NC, 27709
Abstract:To estimate model parameters from complex sample data. we apply maximum likelihood techniques to the complex sample data from the finite population, which is treated as a sample from an i nfinite superpopulation. General asymptotic distribution theory is developed and then applied to both logistic regression and discrete proportional hazards models. Data from the Lipid Research Clinics Program areused to illustrate each model, demonstrating the effects on inference of neglecting the sampling design during parameter estimation. These empirical results also shed light on the issue of model-based vs. design-based inferences.
Keywords:complex survey data  regression  survival analysis  proportional hazards
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