The optimal group size using inverse binomial group testing considering misclassification

ABSTRACT

Inverse binomial sampling is preferred for quick report. It is also recommended when the population proportion is really small to ensure a positive sample is contained. Group testing has been discussed extensively under binomial model, but not so much under negative binomial model. In this study, we investigate the problem of how to determine the group size using inverse binomial group testing. We propose to choose the optimal group size by minimizing asymptotic variance of the estimator or the cost relative to Fisher information. We show the good performance of our estimator by applying to the data of Chlamydia.