Biostatistics:a difficult road ahead

We are now well into the nineteen-eighties and looking back over the last ten years one of the most striking, perhaps the most striking, aspect of biostatistics and statistical epidemiology is sheer volume of literature that has emerged. Any historian of our subject is bound to ask two major and not unrelated questions! how much of this was necessary and how much of it was of direct use to clinical science in the sense of giving real aid to progress in medicine?.