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Estimation of parameters of a polynomial model under intra class correlation structure for incomplete longitudinal data |
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| Authors: | Anand K Seth Sati Mazumdar |
| Institution: | 1. Dept. of Community Medicine , University of Pittsburgh , Cleft Palate Center Children's Hospital of Pittsburgh, Pittsburgh, PA, 15261;2. Dept. of Biostatistics , University of Pittsburgh , Pittsburgh, PA, 15261 |
| Abstract: | The problem of analyzing and modeling incomplete longitudinal data arising from clinical and epidemiological studies are discussed, A method for handling arbitrarily missing observations under the intra class correlation structure and a polynomial model is developed. Explicit expressions for likelihood equations and information matrix for a second degree polynomial model are provided. The method is illustrated through an example. |
| Keywords: | Incomplete longitudinal data polynomial model intra class correlation maximum likelihood estimates |