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A test of the missing data mechanism for repeated measures data
Authors:Taesung Park  Seungyeoun Lee  Robert F Woolson
Institution:1. Department of Statistics , Hankuk University of Foreign Studies , Dongdaemun-Gu, Seoul, 130-791, Korea;2. Department of Applied Statistics , King Sejong University , Sungdong-Gu, Seoul, 133-747, Korea;3. Department of Preventive Medicine and Environmental Health , University of Iowa , Iowa City, IA, 52241
Abstract:The occurrence of missing data is an often unavoidable consequence of repeated measures studies. Fortunately, multivariate general linear models such as growth curve models and linear mixed models with random effects have been well developed to analyze incomplete normally-distributed repeated measures data. Most statistical methods have assumed that the missing data occur at random. This assumption may include two types of missing data mechanism: missing completely at random (MCAR) and missing at random (MAR) in the sense of Rubin (1976). In this paper, we develop a test procedure for distinguishing these two types of missing data mechanism for incomplete normally-distributed repeated measures data. The proposed test is similar in spiril to the test of Park and Davis (1992). We derive the test for incomplete normally-distribrlted repeated measures data using linear mixed models. while Park and Davis (1992) cleirved thr test for incomplete repeatctl categorical data in the framework of Grizzle Starmer. and Koch (1969). Thr proposed procedure can be applied easily to any other multivariate general linear model which allow for missing data. The test is illustrated using the hip-replacernent patient.data from Crowder and Hand (1990).
Keywords:EM algorithm  Likelihood ratio test statistic  Longitudinal data  Missing data  Repeated measures design
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