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Testing equality of regression coefficients in heteroscedastic normal regression models
Institution:1. Department of Diagnostic and Interventional Radiology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-0021, Japan;2. Department of Radiology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan;3. Department of Biomedical Informatics, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan;4. Department of Physiology and Biophysics, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan;1. Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Republic of Korea;2. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea;3. Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;4. Department of Orthopaedic Surgery, Chung-Ang University Hospital, Seoul, Republic of Korea;5. College of Pharmacy Gachon University, Incheon, Republic of Korea;6. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea;1. Canadian Forest Service, Natural Resources Canada, 506 West Burnside Rd., Victoria, BC V8Z 1M5, Canada;2. Department of Ecology and Natural Resource Management, Norwegian University of Life Sciences, P.O. Box 5003, NO 1432 Ås, Norway;3. Forest Research Institute, Wonnhaldestraße 4, Baden-Württemberg 79100, Freiburg, Germany;4. Office National des Forêts, Département RDI, Pôle de Nancy, 11 Ile-de-Corse, 54000, Nancy, France
Abstract:This article addresses the problem of testing whether the vectors of regression coefficients are equal for two independent normal regression models when the error variances are unknown. This problem poses severe difficulties both to the frequentist and Bayesian approaches to statistical inference. In the former approach, normal hypothesis testing theory does not apply because of the unrelated variances. In the latter, the prior distributions typically used for the parameters are improper and hence the Bayes factor-based solution cannot be used.We propose a Bayesian solution to this problem in which no subjective input is considered. We first generate “objective” proper prior distributions (intrinsic priors) for which the Bayes factor and model posterior probabilities are well defined. The posterior probability of each model is used as a model selection tool. This consistent procedure of testing hypotheses is compared with some of the frequentist approximate tests proposed in the literature.
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