Breaking in a new function for casein kinase 2 |
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| Authors: | Morales Julio C Carpenter Phillip B |
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| Institution: | Department of Biochemistry and Molecular Biology, University of California, University of Texas-Houston Medical School, Houston, TX 77225, USA. |
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| Abstract: | DNA damage response mechanisms help ensure the fidelity of chromosomal transmission, and the failure of such mechanisms might lead to premature aging and cancer. A new report has established that casein kinase 2 (CK2), a protein that functions in diverse cellular processes, controls the activity of the DNA repair protein XRCC1. These results indicate that CK2 is a key participant in the cellular response to DNA damage. |
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