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Center and Distinguisher for Strings with Unbounded Alphabet
Authors:Xiaotie Deng  Guojun Li  Lusheng Wang
Institution:(1) Department of Computer Science, City University of Hong Kong, Hong Kong, People's Republic of China;(2) School of Mathematics and System Science, Shandong University, Jinan, 250100, People's Republic of China;(3) Department of Computer Science, City University of Hong Kong, Hong Kong, People's Republic of China
Abstract:Consider two sets 
$$\mathcal{B}$$
and 
$$\mathcal{G}$$
of strings of length L with characters from an unbounded alphabet Sgr, i.e., the size of Sgr is not bounded by a constant and has to be taken into consideration as a parameter for input size. A closest string s* of 
$$\mathcal{B}$$
is a string that minimizes the maximum of Hamming1 distance(s, s*) over all string s : s isin 
$$\mathcal{B}$$
. In contrast, a farthest string t* from 
$$\mathcal{G}$$
maximizes the minimum of Hamming distance(t*,t) over all elements t: t isin 
$$\mathcal{G}$$
. A distinguisher of 
$$\mathcal{B}$$
from 
$$\mathcal{G}$$
is a string that is close to every string in 
$$\mathcal{B}$$
and far away from any string in 
$$\mathcal{G}$$
. We obtain polynomial time approximation schemes to settle the above problems.
Keywords:approximation algorithm  computational molecular biology  center string selection  distinguishing string selection  unbounded alphabet size
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