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Block designs for incomplete factorial treatment structures with two factors
Abstract:Abstract

In this paper, the problem of obtaining efficient block designs for incomplete factorial treatment structure with two factors excluding one treatment combination for estimation of dual versus single treatment contrasts is considered. The designs have been obtained using the A-optimal completely randomized designs and modified strongest treatment interchange algorithm. A catalog of efficient block designs has been prepared for m1?=?3, 4 and m2?=?2, b?≤?10 and k?≤?9 and for m1?=?3,4 and m2?=?3, 4, b?≤?10 and k?≤?10.
Keywords:Block designs  A-efficiency  incomplete factorial treatment structures  strongest treatment interchange  dual versus single treatment contrasts  placebo controlled clinical trial
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