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The Identifiability of Dependent Competing Risks Models Induced by Bivariate Frailty Models
Authors:Antai Wang  Krishnendu Chandra  Ruihua Xu  Junfeng Sun
Institution:1. Department of Mathematical SciencesNew Jersey Institute of Technology;2. Department of BiostatisticsColumbia University;3. National Human Genome Research InstituteNational Institutes of Health;4. Critical Care Medicine Department, Clinical CenterNational Institutes of Health
Abstract:In this paper, we propose to use a special class of bivariate frailty models to study dependent censored data. The proposed models are closely linked to Archimedean copula models. We give sufficient conditions for the identifiability of this type of competing risks models. The proposed conditions are derived based on a property shared by Archimedean copula models and satisfied by several well‐known bivariate frailty models. Compared with the models studied by Heckman and Honoré and Abbring and van den Berg, our models are more restrictive but can be identified with a discrete (even finite) covariate. Under our identifiability conditions, expectation–maximization (EM) algorithm provides us with consistent estimates of the unknown parameters. Simulation studies have shown that our estimation procedure works quite well. We fit a dependent censored leukaemia data set using the Clayton copula model and end our paper with some discussions. © 2014 Board of the Foundation of the Scandinavian Journal of Statistics
Keywords:Archimedean copula models  bivariate frailty models  competing risks models  discrete covariates  identifiability
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