The impact of age,BMI and sex hormone on aging males’ symptoms and the international index of erectile function scores |
| |
Authors: | Xiao-Hua Yu Jing Zhao Shu-Cheng Zhang Jian-Hui Li Jun-Biao Zheng Zheng Li |
| |
Institution: | 1. Department of Urology, The First People’s Hospital of Jiashan, Jiaxing, Zhejiang, China;2. Department of Reproductive Epidemiology and Social Science, Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China;3. Department of Cell Biology, National Research Institute of Family Planning, Beijing, China;4. Department of Andrology, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China |
| |
Abstract: | Objective: To analyze the impact of age, BMI and sex hormone on aging males’ symptoms (AMS) and the 5-item version of the international index of erectile function (IIEF-5) scores in middle-aged and elderly Chinese men.Methods: A population-based cross-sectional study was conducted in Jiashan County. A total of 969 men, aged between 40 and 80 years old, were admitted. Physical examination and the sex hormones were measured, and AMS and IIEF-5 scores were assessed.Results: The oneway ANOVA analysis indicated older age groups had higher AMS total-scores, somatic and sexual sub-scores, and lower IIEF5 scores (all p?.01). Pairwise correlation (rpairwise) analyses showed the significant associations between AMS and age or sex hormone (cFT, Bio-T, SHBG, and LH) levels, and similar for IIEF5. However, when age was adjusted, the correlation coefficients (rpartial) weakened, and correlation significance disappeared, except LH (for AMS: rpartial?=?0.096, p?=?.009; for IIEF-5: rpartial?= ?0.140, p?=?.001). Multiple linear regressions confirmed the influence of increased age and LH on the AMS and IIEF5 scores.Conclusion: CFT, Bio-T and SHBG failed to yield any additional predicting information when age was adjusted. To improve the male reproductive health, future research should pay more attention on aging-related comorbidities and how to improve general wellness. |
| |
Keywords: | Aging androgenic sex hormone erectile dysfunction aging males’ symptoms body mass index |
|
|