| 辛伐他汀对血脂正常的急性冠脉综合征患者炎症因子及预后的影响 |
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| 引用本文： | 卢杰. 辛伐他汀对血脂正常的急性冠脉综合征患者炎症因子及预后的影响[J]. 西南科技大学学报(哲学社会科学版), 2009, 7(2): 99-100 |
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| 作者姓名： | 卢杰 |
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| 作者单位： | 沈阳医学院沈洲医院,110002 |
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| 摘 要： | 目的观察血脂正常的急性冠脉综合征（ACS）早期应用辛伐他汀对C反应蛋白（CRP）及心血管事件发生的影响。方法将64例血脂正常的急性冠脉综合征患者随机分为治疗组（n=32除常规治疗外加服辛伐他汀20mg）和对照组（n=32仅常规治疗）,于治疗前、治疗4w后观察C反应蛋白变化,心血管事件发生次数。结果治疗组于治疗后CRP有明显下降（1.76mg/L对2.11mg/L,P〈0.05）,并明显低于对照组（1.76mg/L对2.08mg/L,P〈0.05）,心血管事件也明显少于对照组（9.4%对31.3%,P〈0.05）。结论辛伐他汀对血脂正常的ACS早期治疗能明显降低CRP水平,抑制炎症反应,稳定易损斑块,减少心血管事件的发生。
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| 关 键 词： | 辛伐他汀 血脂 急性冠脉综合征C反应蛋白 心血管事件 |
The effects of simvastatin on inflammation facrors in patients with mean serum lipid in acute coronary artery syndrome(ACS) |
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| LV Jie. The effects of simvastatin on inflammation facrors in patients with mean serum lipid in acute coronary artery syndrome(ACS)[J]. Journal of Southwest University of Science and Technology, 2009, 7(2): 99-100 |
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| Authors: | LV Jie |
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| Affiliation: | LV Jie.Shenzhou Hospital of Shenyang Medical College,Shenyang 110002,China. |
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| Abstract: | Objective To evaluate the effection of Simvastatin on C-reactive protein(CRP) and the cardiovascular attacts in the patients with ACS,however,without dyslipidemia.Method A cohort of 64 patients with ACS but mean serum lipid was randomly assigned to Simvastatin group(n=32 Simvastatin 20mg based on routine treatment) and control group(n=32 only received routine treatment).Recorded the change of CRP and number of cadouvascular attacts before and 4 weeks after treatment.Results CRP in Simvastatin group signific... |
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| Keywords: | Simvastatin Serum lipid Acute Coronary Artery Syndrome C-reactive protein Cadiovascular attacts |
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