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Two Statistics for Unconditional Exact Tests in Matched-Pairs Design
Abstract:Abstract

In a recent article Hsueh et al. (Hsueh, H.-M., Liu, J.-P., Chen, J. J. (2001 Hsueh, H.-M., Liu, J.-P. and Chen, J. J. 2001. Unconditional exact tests for equivalence or noninferiority for paired binary endpoints. Biometrics, 57: 478483. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Unconditional exact tests for equivalence or noninferiority for paired binary endpoints. Biometrics 57:478–483.) considered unconditional exact tests for paired binary endpoints. They suggested two statistics one of which is based on the restricted maximum-likelihood estimator. Properties of these statistics and the related tests are treated in this article.
Keywords:Trinomial distribution  Barnard's property C  Unconditional p-value  Sample-based statistic  RMLE statistic
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