立普妥对老年充血性心力衰竭MS患者血清CRP和LDL-C的影响

目的探讨CRP水平和充血性心力衰竭（CHF）、代谢综合征（MS）程度之间的关系,以及应用立普妥对CHF代谢综合征预后的影响。方法观察120例CHF代谢综合征患者在常规应用心衰治疗药物的基础上,给予立普妥干预前后血清CRP和LDL-C的变化。另选30例无心衰MS患者为对照组。结果心衰代谢综合征患者CRP、LDL-C水平均明显高于无心衰代谢综合征患者（P〈0.05）相关分析显示CHF患者的CRP水平和心衰程度呈正相关（r=0.14,0.21,0.32,0.39,P〈0.05）。CHF患者的LDL-C水平和心衰程度亦呈正相关（r=0.21,0.33,0.46,0.50,P〈0.05）。药物干预组立普妥治疗前与治疗后比较,LDL-C水平有明显降低（P〈0.05）。常规治疗组治疗前与治疗后比较,LDL-C水平无明显变化（P〉0.05）。药物干预组患者给予立普妥干预治疗4,8周后比较CRP水平均有显著降低（P〈0.01）,且与应用时间的长短呈正相关（r=0.11,0.34,P〈0.05）;常规治疗组患者治疗前、后比较,CRP水平无明显变化（P〉0.05）。结论CRP可以作为CHF代谢综合征患者预后评估的重要指标之一。     

分层服务集成架构及其关键技术的研究

本文针对异构信息系统集成问题，结合面向服务的体系结构（SOA）的设计思想和实现技术，提出了分层服务集成架构（LSI）。LSI系统考虑了从客户访问到数据获取，乃至安全认证的信息系统应用的各个层面；不同的层次解决不同的集成问题；将设计模式融入到集成架构中，使得集成各层之间达到松散耦合和良好的互操作性，并详细阐述了集成架构每一层次的支撑技术和设计、实现方法。     

Exact inference for a simple step-stress model with competing risks for failure from exponential distribution under Type-II censoring

In reliability analysis, accelerated life-testing allows for gradual increment of stress levels on test units during an experiment. In a special class of accelerated life tests known as step-stress tests, the stress levels increase discretely at pre-fixed time points, and this allows the experimenter to obtain information on the parameters of the lifetime distributions more quickly than under normal operating conditions. Moreover, when a test unit fails, there are often more than one fatal cause for the failure, such as mechanical or electrical. In this article, we consider the simple step-stress model under Type-II censoring when the lifetime distributions of the different risk factors are independently exponentially distributed. Under this setup, we derive the maximum likelihood estimators (MLEs) of the unknown mean parameters of the different causes under the assumption of a cumulative exposure model. The exact distributions of the MLEs of the parameters are then derived through the use of conditional moment generating functions. Using these exact distributions as well as the asymptotic distributions and the parametric bootstrap method, we discuss the construction of confidence intervals for the parameters and assess their performance through Monte Carlo simulations. Finally, we illustrate the methods of inference discussed here with an example.     

基于工具-目标法的经济政策效应评价研究

经济政策评价不仅指政策决策评价，还应包括对政策执行效果进行评价，即效应评价。但目前在计量经济学的研究中，包括已出版的各类教科书中也都只给出了如何进行决策评价的方法，而没有对效应评价方法进行研究。这显然是欠缺的。采用经济计量分析法对经济决策评价，常用的方法有三种：工具-目标法（TOM）、最优控制法、政策模拟法。其中工具-目标法是最早用来进行政策决策评价的计量方法，它是由首届诺贝尔经济学奖得主之一丁伯根提出的。     

苏轼的"枯淡"论研究——兼论"东坡和陶诗"的文化史意义

苏轼对"平淡"风格的认识,主要体现在他对陶渊明诗歌"枯淡"美的批评上。"枯淡"风格的形成是一个"绚烂之极归于平淡"的过程,体现在陶渊明的诗歌中就是"质而实绮,癯而实腴"、"外枯而中膏,似淡而实美"的美学效果。从"枯淡"风格出发,苏轼发现了柳宗元、韦应物诗风与陶渊明"同源",并作出了"柳在韦上"的判断。苏轼还创作了大量的"和陶诗",这在中国古代文化史上具有重要的认识价值。     

Estimating the Upper Support Point in Deconvolution

Abstract.  We consider estimation of the upper boundary point F ⁻¹ (1) of a distribution function F with finite upper boundary or 'frontier' in deconvolution problems, primarily focusing on deconvolution models where the noise density is decreasing on the positive halfline. Our estimates are based on the (non-parametric) maximum likelihood estimator (MLE) of F . We show that (1) is asymptotically never too small. If the convolution kernel has bounded support the estimator (1) can generally be expected to be consistent. In this case, we establish a relation between the extreme value index of F and the rate of convergence of (1) to the upper support point for the 'boxcar' deconvolution model. If the convolution density has unbounded support, (1) can be expected to overestimate the upper support point. We define consistent estimators , for appropriately chosen vanishing sequences ( β _n ) and study these in a particular case.     

Some preservation results of NBUC aging property with applications

This paper develops a new characterization of NBUC aging property, and investigates its preservation properties both under monotonic anti-star-shaped transformations and under the non-homogeneous Poisson shock models.     

粤苏辽京四省市农村土地股份合作制改革及其启示

粤苏辽京四省(市)在农村土地(社区)股份合作制改革方面走在全国的前列,富有特色性和典型性,值得参考和借鉴。本文在广泛调研的基础上,总结了四省(市)农村土地(社区)股份合作制改革的基本情况和特点,探讨了改革过程中具有规律性的东西及四省(市)经验对于推进农村土地(社区)股份合作制改革的若干启示。     

重庆绕城高速公路北段水土保持生态修复措施

在对绕城高速公路北段自然条件、水土流失特点和沿线水土保持措施综合分析的基础上,基于宫胁法生态修复原理,提出绕城高速公路北段水土保持生态修复3个原则,分5个功能区建立水土保持生态修复措施体系,以实现高速公路"点、线、面"水土保持综合防护目标,对高速公路水土保持生态修复措施监测重点也进行了探讨。     

清代司法实践中的推类方法与民间规范

将民间规范引入司法过程以正当化案件裁决,是和谐司法的内在要求。清代司法官运用推类方法,将民间规范引入司法实践中以填补法律漏洞,正当化案件裁决,这对和谐司法的建设,具有借鉴意义。当下将风俗习惯运用于司法实践,在运用类比推理解决疑难案件过程中,必须借鉴推类方法的优长之处,以弥补类比推理的不足之处。唯有如此,才能弥补法律漏洞,解决疑难案件,提高判决的正当性和说服力,才能真正将裁判的法律效果和社会效果结合起来,达致司法和谐。