Semiparametric regression of clustered current status data

This paper discusses regression analysis of clustered current status data under semiparametric additive hazards models. In particular, we consider the situation when cluster sizes can be informative about correlated failure times from the same cluster. To address the problem, we present estimating equation-based estimation procedures and establish asymptotic properties of the resulting estimates. Finite sample performance of the proposed method is assessed through an extensive simulation study, which indicates the procedure works well. The method is applied to a motivating data set from a lung tumorigenicity study.     

The effects of individually varying times of observations on growth parameter estimations in piecewise growth model

When using latent growth modeling (LGM), researchers often restrict the factor loadings, while the multilevel modeling (MLM) treats time as a metric variable. However, when individually varying times of observations are concerned in the longitudinal studies, the use of specified loadings would lead to inaccurate estimation. Based on piecewise growth modeling (PGM), this simulation study showed that (i) individually varying times of observations with larger boundaries got worse estimates and model fits when LGM was used; (ii) estimating the PGM across all the simulation situations was robust within MLM, whereas LGM got identically equal estimation with MLM only in the case of time boundaries of ±1 month or shorter; (iii) larger change of slope in piecewise modeling indicated better estimation.     

A class of additive transformation models for recurrent gap times

Abstract

The gap time between recurrent events is often of primary interest in many fields such as medical studies, and in this article, we discuss regression analysis of the gap times arising from a general class of additive transformation models. For the problem, we propose two estimation procedures, the modified within-cluster resampling (MWCR) method and the weighted risk-set (WRS) method, and the proposed estimators are shown to be consistent and asymptotically follow the normal distribution. In particular, the estimators have closed forms and can be easily determined, and the methods have the advantage of leaving the correlation among gap times arbitrary. A simulation study is conducted for assessing the finite sample performance of the presented methods and suggests that they work well in practical situations. Also the methods are applied to a set of real data from a chronic granulomatous disease (CGD) clinical trial.     

中日史前拔牙年龄和次数比较研究

探讨史前拔牙个体的年龄和次数,对了解史前社会生活和社会意识、宗教信仰具有重要意义。认为中国和日本新石器时代的原生拔牙应该是青春期或成年期拔牙。中国新石器时代只存在一次拔牙现象,而日本新石器时代存在多次拔牙现象。这说明虽然同处新石器时代,但社会结构和社会意识有所不同。     

Investigating the impact of violations of the “left and top means first” heuristic on response behavior and data quality

ABSTRACT

Web surveys are an established data collection mode that use written language to provide information. The written language is accompanied by visual elements, such as presentation formats and shapes. However, research has shown that visual elements influence response behavior because respondents sometimes use interpretive heuristics to make sense of the visual elements. One such heuristic is the ‘left and top means first’ (LTMF) heuristic, which suggests that respondents tend to believe that a response scale consistently runs from left to right or from top to bottom. We conducted a web survey experiment to investigate how violations of the LTMF heuristic affect response behavior and data quality. For this purpose, a random half of respondents received response options that followed a consistent order and the other half received response options that followed an inconsistent order. The results reveal significantly different response distributions between the two groups. We also found that inconsistently ordered response options significantly increase response times and decrease data quality in terms of criterion validity. We, therefore, recommend using options that follow the design strategies of the LTMF heuristic.     

Joint Modelling of Survival and Longitudinal Data with Informative Observation Times

In this paper, we consider the joint modelling of survival and longitudinal data with informative observation time points. The survival model and the longitudinal model are linked via random effects, for which no distribution assumption is required under our estimation approach. The estimator is shown to be consistent and asymptotically normal. The proposed estimator and its estimated covariance matrix can be easily calculated. Simulation studies and an application to a primary biliary cirrhosis study are also provided.     

A class of partially linear transformation models for recurrent gap times

In this article, we propose a general class of partially linear transformation models for recurrent gap time data, which extends the linear transformation models by incorporating non linear covariate effects and includes the partially linear proportional hazards and the partially linear proportional odds models as special cases. Both global and local estimating equations are developed to estimate the parametric and non parametric covariate effects, and the asymptotic properties of the resulting estimators are established. The finite-sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a clinic study on chronic granulomatous disease is provided.     

怒俅殖边:近代云南一次意义深远的边疆开发

民国初期 ,云南地方政府在滇西北怒江少数民族地区的设治经营 ,是云南边疆民族地区发展历史上的一个重大事件 ,它对怒江地区的社会发展和各民族的进步产生了极其重大而深远的影响。本文阐述了“怒俅殖边”这一历史进程 ,认为它使怒江地区的民族关系得到明显的调整与改善 ;使怒江经济社会发展进入一个新时期 ;遏制了英国侵略势头 ,对巩固滇西北边防产生了重要和深远的影响     

近代广东商业人群在广西的分布面及其梯度差考详——粤港商业经济对广西经济辐射研究之二

文章从中国近代史上城镇经济主体——商业经济的角度切入,运用各类历史资料,分区逐县地确证广东商业人群以及所造成的“无东不成市”格局在全广西的分布范围,并揭示其在广西不同地域的程度等差和梯度分布状态。从而,以原始的生活场景原生态地呈现出粤港澳地区对广西经济辐射由东而西逐步推进、由城市而圩市逐层次渗透的基本节奏和客观规律。     

浅论近代青海女性社会地位变迁及其原因

近代是青海女性社会地位发生变迁的时期,本文从女性形体观的转变、女性教育等方面,论述了近代青海女性社会地位的变迁及其原因。