AbstractObjective: The current study aims to validate the PERMA-Profiler, a well-known well-being measure, among a sample of student veterans. Participants: A sample of 205 student veterans were recruited from universities across the United States. Method: Cross-sectional research design was used in this study. Measurement structure of the PERMA-Profiler was evaluated using exploratory factor analysis (EFA). Convergent, divergent, and criterion-related validity was tested using Pearson correlation coefficients and Kruskal-Wallis test. Results: The EFA results yielded a two-factor solution for student veterans. Factors are named as emotional character strengths and performance character strengths. Conclusions: The PERMA-Profiler is a multidimensional scale with good reliability and acceptable levels of convergent, divergent, and criterion-related validity. The PERMA-Profiler can help researchers and practitioners better gauge well-being in student veterans. Implications will be discussed. 相似文献
Previous studies have shown a negative relationship between loneliness and one’s subjective well-being. However, it has not been fully examined within the Chinese context which highlights the importance of social relationship and interpersonal harmony for one’s life, and the mechanism between them has not been thoroughly explored. Based on social cognitive theory, this study examined the main effects of loneliness on individuals’ stress, depression, and life satisfaction, as well as the mediating effect of self-efficacy between them. Survey data were obtained from 444 Chinese undergraduates. The results of multiple regressions revealed that loneliness was negatively correlated with life satisfaction and positively correlated with stress and depression. Moreover, self-efficacy partially mediated the relationship between loneliness and stress, as well as depression, and fully mediated the relationship between loneliness and life satisfaction. Implications for research and practice are discussed.
In late-phase confirmatory clinical trials in the oncology field, time-to-event (TTE) endpoints are commonly used as primary endpoints for establishing the efficacy of investigational therapies. Among these TTE endpoints, overall survival (OS) is always considered as the gold standard. However, OS data can take years to mature, and its use for measurement of efficacy can be confounded by the use of post-treatment rescue therapies or supportive care. Therefore, to accelerate the development process and better characterize the treatment effect of new investigational therapies, other TTE endpoints such as progression-free survival and event-free survival (EFS) are applied as primary efficacy endpoints in some confirmatory trials, either as a surrogate for OS or as a direct measure of clinical benefits. For evaluating novel treatments for acute myeloid leukemia, EFS has been gradually recognized as a direct measure of clinical benefits. However, the application of an EFS endpoint is still controversial mainly due to the debate surrounding definition of treatment failure (TF) events. In this article, we investigate the EFS endpoint with the most conservative definition for the timing of TF, which is Day 1 since randomization. Specifically, the corresponding non-proportional hazard pattern of the EFS endpoint is investigated with both analytical and numerical approaches. 相似文献
ABSTRACTDrawing on digitaltrace data, publicly accessible government documents, and journalistic reports, this research integrates Beck’s risk society theory with digital media theories to examine the mediated process of risk definition and assessment of PM2.5 (particulate matters with a diameter less than 2.5 micrometers) in a networked public sphere. Network and content analysis of a PM2.5 Twitter network shows that political and professional elite remained the most powerful producers of risk definition. Established media played a key role, yet faced challenges from a variety of actors who disseminated and filtered information. Laypersons, while peripheral, actively interacted with elite and established media. The blurring geographic boundary in the PM2.5 Twitter network revealed an emerging transnational public sphere, which, however, was segregated by language. This research advances a layered understanding of the contingent, paradoxical media impact for social changes in a risk society. 相似文献
Although Asian American youth are often viewed as the model minority group who are doing well, research with youths, parents, and school personnel have documented significant unmet mental health needs among this population. However, little is known about the perspectives of service providers who work with Asian American youth in afterschool and mental health care settings with respect to what they perceive as challenges meeting the psychosocial needs of the population. The current exploratory study used Consensual Qualitative Research to analyze in-depth interviews with mental health providers, educators, and advocates working with Asian American youths in a multiethnic large urban environment. Results found that service providers were attuned to the multiple needs of the community but also spoke of challenges in meeting basic and psychological needs due to difficult family dynamics, structural stressors (e.g., economic and legal), and societal stigma and discrimination. We draw implications for providing more integrated services across different levels of urban Asian American adolescents’ ecological system to better meet the psychosocial challenges facing this population. 相似文献